Steps to razor-sharp imaging inside 3D cell models

EVIDENT Europe GmbH

The optimal lens delivers an accurate view inside 3D models

Tissue clearing and objective selection explained in simple terms

Spheroids and organoids are excellent in vivo models for complex biochemical processes. However, light scattering of internal cellular compartments is a major challenge for imaging techniques. A variety of tissue clearing techniques are available to make tissue models transparent. Find out what you need to consider in order to obtain high-resolution images without affecting model morphology.

Download this free application note and learn how to:

  • optimally prepare 200-300 µm thick spheroids and organoids for 3D imaging in a single step, using tissue clearing techniques
  • obtain razor-sharp images thanks to an objective with a matching refractive index,
  • perform quantitative 3D analyses with smart cell analysis software such as NoviSight.

Download white paper now

The optimal lens delivers an accurate view inside 3D models

Steps to razor-sharp imaging inside 3D cell models

Tissue clearing and objective selection explained in simple terms

EVIDENT Europe GmbH
All about EVIDENT

See the theme worlds for related content

Topic World Cell Analysis

Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.

10+ products
5+ whitepaper
10+ brochures
View topic world
Topic World Cell Analysis

Topic World Cell Analysis

Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.

10+ products
5+ whitepaper
10+ brochures

Last viewed contents

Obtain quantitative results from your cell cultures – automatically and non-invasively - Learn how to easily improve your experiment reproducibility

Obtain quantitative results from your cell cultures – automatically and non-invasively - Learn how to easily improve your experiment reproducibility

A troubleshooting guide to microplate-based assays - Understand the impact microplate features and microplate reader settings have on your results

A troubleshooting guide to microplate-based assays - Understand the impact microplate features and microplate reader settings have on your results

How is High-Throughput Multi-Parameter Flow Cytometry used in Biopharma? - Learn how Biopharma industry experts apply flow cytometry in Drug Discovery & Development

How is High-Throughput Multi-Parameter Flow Cytometry used in Biopharma? - Learn how Biopharma industry experts apply flow cytometry in Drug Discovery & Development

RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR - Transforming Bioanalysis of RNA Therapeutics, from Discovery and Development to Manufacturing QC

RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR - Transforming Bioanalysis of RNA Therapeutics, from Discovery and Development to Manufacturing QC

Accurate and reliable cell counting using holographic microscopy and machine learning algorithms - In this study, we evaluated the performance of a cell counter according to the CLSI EP05-A32.

Accurate and reliable cell counting using holographic microscopy and machine learning algorithms - In this study, we evaluated the performance of a cell counter according to the CLSI EP05-A32.

How excessive fat tissue affects our blood vessels - New insights into vascular health in obesity

How excessive fat tissue affects our blood vessels - New insights into vascular health in obesity

New Label-Free Imaging Tracks Cancer Treatment in Single Cells - One Tool, Many Applications

New Label-Free Imaging Tracks Cancer Treatment in Single Cells - One Tool, Many Applications

Attracting bright and bold minds: new ideas for genome diagnostics and single molecule sensing - Four innovative life sciences ideas with particular economic potential receive awards

Attracting bright and bold minds: new ideas for genome diagnostics and single molecule sensing - Four innovative life sciences ideas with particular economic potential receive awards

New Microscope Brings Glowing Cells into Focus - A New Tool for Studying Life in Motion

New Microscope Brings Glowing Cells into Focus - A New Tool for Studying Life in Motion

CellMOUSE - Ulm, Germany

CellMOUSE - Ulm, Germany

Nanolive SA - Tolochenaz, Switzerland

Nanolive SA - Tolochenaz, Switzerland

Beckman Coulter GmbH - Krefeld, Germany

Beckman Coulter GmbH - Krefeld, Germany